Title : Targeting cancer cells with oleanolic and ursolic acid derived hydroxamates.

Pub. Date : 2016 Feb 1

PMID : 26750249






4 Functional Relationships(s)
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1 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid latexin Homo sapiens
2 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid latexin Homo sapiens
3 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid latexin Homo sapiens
4 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid latexin Homo sapiens