Title : Induction of TNF in vitro as a model for the identification of toxic malaria antigens.

Pub. Date : 1989 Fall

PMID : 2674557






1 Functional Relationships(s)
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1 We have shown that human and rodent blood-stage parasites liberate heat-stable soluble antigens that induce the release of TNF by activated macrophages in vitro and in vivo, and are toxic to mice made hypersensitive to TNF by D-galactosamine. Galactosamine tumor necrosis factor Mus musculus