Pub. Date : 2015
PMID : 26735433
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The HDAC (histone deacetylase) inhibitor valproic acid (VPA) interacted synergistically with chemotherapeutic agents to trigger lymphoma cell autophagy, which resulted from activation of AMPK (AMP-activated protein kinase) and inhibition of downstream MTOR (mechanistic target of rapamycin [serine/threonine kinase]) signaling. | Valproic Acid | mechanistic target of rapamycin kinase | Homo sapiens |
2 | The HDAC (histone deacetylase) inhibitor valproic acid (VPA) interacted synergistically with chemotherapeutic agents to trigger lymphoma cell autophagy, which resulted from activation of AMPK (AMP-activated protein kinase) and inhibition of downstream MTOR (mechanistic target of rapamycin [serine/threonine kinase]) signaling. | Valproic Acid | mechanistic target of rapamycin kinase | Homo sapiens |