Title : Curcumin modulates cell death and is protective in Huntington's disease model.

Pub. Date : 2016 Jan 5

PMID : 26728250






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. polyglutamine huntingtin Drosophila melanogaster
2 Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. polyglutamine huntingtin Drosophila melanogaster
3 Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. polyglutamine huntingtin Drosophila melanogaster
4 Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. polyglutamine huntingtin Drosophila melanogaster
5 In a Drosophila model of HD, expression of mutant Huntingtin (Htt) protein with expanded polyQ leads to formation of inclusion bodies (IBs), increase in cellular toxicity, progression of motor disabilities and reduced viability. polyglutamine huntingtin Drosophila melanogaster
6 In a Drosophila model of HD, expression of mutant Huntingtin (Htt) protein with expanded polyQ leads to formation of inclusion bodies (IBs), increase in cellular toxicity, progression of motor disabilities and reduced viability. polyglutamine huntingtin Drosophila melanogaster