Pub. Date : 2016 Jan 5
PMID : 26728250
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. | polyglutamine | huntingtin | Drosophila melanogaster |
2 | Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. | polyglutamine | huntingtin | Drosophila melanogaster |
3 | Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. | polyglutamine | huntingtin | Drosophila melanogaster |
4 | Huntington"s disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. | polyglutamine | huntingtin | Drosophila melanogaster |
5 | In a Drosophila model of HD, expression of mutant Huntingtin (Htt) protein with expanded polyQ leads to formation of inclusion bodies (IBs), increase in cellular toxicity, progression of motor disabilities and reduced viability. | polyglutamine | huntingtin | Drosophila melanogaster |
6 | In a Drosophila model of HD, expression of mutant Huntingtin (Htt) protein with expanded polyQ leads to formation of inclusion bodies (IBs), increase in cellular toxicity, progression of motor disabilities and reduced viability. | polyglutamine | huntingtin | Drosophila melanogaster |