Title : Using Human iPSC-Derived Neurons to Model TAU Aggregation.

Pub. Date : 2015

PMID : 26720731






2 Functional Relationships(s)
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1 Both rapamycin and trehalose significantly reduced TAU aggregation levels suggesting that iPSC-derived neurons allow for the generation of a biologically relevant human Tauopathy model, highly suitable to screen for compounds that modulate TAU aggregation. Trehalose microtubule associated protein tau Homo sapiens
2 Both rapamycin and trehalose significantly reduced TAU aggregation levels suggesting that iPSC-derived neurons allow for the generation of a biologically relevant human Tauopathy model, highly suitable to screen for compounds that modulate TAU aggregation. Trehalose microtubule associated protein tau Homo sapiens