Title : Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1.

Pub. Date : 2016 Mar

PMID : 26688581






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 While levels of PSD95, glutamate receptor 1 (GluR1), and N-methyl-d-aspartate receptor NR1 subunit (NR1), which are key postsynaptic proteins that regulate synaptic plasticity, were decreased with aging, they were restored by bexarotene treatment in the brains of control but not nLrp1(-/-) mice. Bexarotene discs large MAGUK scaffold protein 4 Mus musculus