Pub. Date : 2016 Apr
PMID : 26679079
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of niacin on triglyceride-rich lipoprotein apolipoprotein B-48 kinetics in statin-treated patients with type 2 diabetes. | Niacin | apolipoprotein B | Homo sapiens |
| 2 | RESULTS: In statin-treated patients with T2DM, apoB-48 concentration was lower with ER niacin (8.24 +- 1.98 vs 5.48 +- 1.14 mg/l, p = 0.03) compared with statin alone. | Niacin | apolipoprotein B | Homo sapiens |
| 3 | Postprandial triglyceride and apoB-48 AUC were also significantly lower on ER niacin treatment (-15 and -26%, respectively; p < 0.05), without any change to triglyceride and apoB-48 iAUC. | Niacin | apolipoprotein B | Homo sapiens |
| 4 | ApoB-48 secretion rate in the basal state (3.21 +- 0.34 vs 2.50 +- 0.31 mg/kg/day; p = 0.04) and number of apoB-48-containing particles secreted in response to the fat load (1.35 +- 0.19 vs 0.84 +- 0.12 mg/kg; p = 0.02) were lower on ER niacin. | Niacin | apolipoprotein B | Homo sapiens |