Title : Pharmacological inhibition of eicosanoids and platelet-activating factor signaling impairs zymosan-induced release of IL-23 by dendritic cells.

Pub. Date : 2016 Feb 15

PMID : 26673542






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 DC showed a high expression and detectable Ser663 phosphorylation of 5-lipoxygenase in response to zymosan, and a high expression and activity of LPCAT1/2 (lysophosphatidylcholine acyltransferase 1 and 2), the enzymes that incorporate acetate from acetyl-CoA into choline-containing lysophospholipids to produce PAF. Zymosan arachidonate 5-lipoxygenase Homo sapiens