Title : Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes.

Pub. Date : 2016 Dec

PMID : 26671617






1 Functional Relationships(s)
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1 However, the activation of the indoleamine-2,3-dioxygenase (IDO), an enzyme that participate of the tryptophan metabolism leading to a decrease of serotonin (5-HT) levels and whose expression is associated with an immune system activation, has been proposed as a common mechanism that links depression and diabetes. Tryptophan indoleamine 2,3-dioxygenase 1 Rattus norvegicus