Title : Inhibitory Effect of Memantine on Streptozotocin-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Neurotrophic Factor Decline in Astrocytes.

Pub. Date : 2016 Dec

PMID : 26660109






1 Functional Relationships(s)
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1 In addition, memantine also displays protective effects against STZ-induced astrocyte activation showed by reduction of inflammatory markers, nuclear factor kappa-B translocation, glial fibrillary acidic protein, cyclooxygenase-2, tumor necrosis factor-alpha level, and oxidative-nitrostative stress. Memantine prostaglandin-endoperoxide synthase 2 Homo sapiens