Title : Protective effects of madecassoside against Doxorubicin induced nephrotoxicity in vivo and in vitro.

Pub. Date : 2015 Dec 14

PMID : 26658818






2 Functional Relationships(s)
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1 Further studies with application of iNOS inhibitor and ERK1/2 kinase inhibitor indicated that the inhibitory effects of MA on DOX-induced apoptosis and inflammation might be mediated by the suppression of the activation of cleaved caspase-3, ERK1/2 pathways, NF-kappaB p65 and NO production. Doxorubicin mitogen-activated protein kinase 3 Homo sapiens
2 Further studies with application of iNOS inhibitor and ERK1/2 kinase inhibitor indicated that the inhibitory effects of MA on DOX-induced apoptosis and inflammation might be mediated by the suppression of the activation of cleaved caspase-3, ERK1/2 pathways, NF-kappaB p65 and NO production. Doxorubicin mitogen-activated protein kinase 3 Homo sapiens