Pub. Date : 2016 Jan
PMID : 26657057
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Either co-transfection with Pirt or intracellular application of PIP2 (but not PI) significantly enhanced menthol-induced TRPM8 currents. | Phosphatidylinositol 4,5-Diphosphate | transient receptor potential cation channel subfamily M member 8 | Homo sapiens |
| 2 | Furthermore, Pirt and PIP2 synergistically modulated menthol-induced TRPM8 currents. | Phosphatidylinositol 4,5-Diphosphate | transient receptor potential cation channel subfamily M member 8 | Homo sapiens |
| 3 | CONCLUSION: Pirt and PIP2 synergistically enhance TRPM8 channel activity, and Pirt regulates TRPM8 channel activity by increasing the single channel conductance. | Phosphatidylinositol 4,5-Diphosphate | transient receptor potential cation channel subfamily M member 8 | Homo sapiens |