Title : Roles of NMDARs in maintenance of the mouse cerebrovascular endothelial cell-constructed tight junction barrier.

Pub. Date : 2016 Jan 2

PMID : 26655082






2 Functional Relationships(s)
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1 As to the mechanism, NMDA stimulated sequential phosphorylations of extracellular signal-regulated kinase (ERK)1/2 and mitogen-activated ERK (MEK)1. N-Methylaspartate mitogen-activated protein kinase 3 Mus musculus
2 The NMDA-induced alterations in ERK1/2 phosphorylation and occludin levels were reversed by pretreatment with PD98059, a MEK inhibitor, and MK-801, a NMDAR antagonist, respectively. N-Methylaspartate mitogen-activated protein kinase 3 Mus musculus