Title : Uncommon dihydropyrimidine dehydrogenase mutations and toxicity by fluoropyrimidines: a lethal case with a new variant.

Pub. Date : 2016

PMID : 26651493






1 Functional Relationships(s)
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1 DPD is the rate-limiting enzyme involved in the metabolism of 5-fluorouracil and its prodrugs, capecitabine and tegafur. Tegafur dihydropyrimidine dehydrogenase Homo sapiens