Title : LY294002 prevents lipopolysaccharide‑induced hepatitis in a murine model by suppressing IκB phosphorylation.

Pub. Date : 2016 Jan

PMID : 26647861






1 Functional Relationships(s)
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1 In LPS-induced hepatitis, treatment with LY294002 clearly inhibited intrahepatic synthesis of various disease-relevant proinflammatory cytokines, including tumor necrosis factor-alpha, interleukin (IL)-6, IL-1beta and interferon-gamma. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one interleukin 1 beta Mus musculus