Pub. Date : 2015
PMID : 26639720
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, taking acyclic derivatives of 6-methyluracil as a model AChE inhibitor, we attempted to develop AChE inhibitors that specifically bind to the PAS with weak binding to the active site of AChE. | Aminosalicylic Acid | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | In the present study, taking acyclic derivatives of 6-methyluracil as a model AChE inhibitor, we attempted to develop AChE inhibitors that specifically bind to the PAS with weak binding to the active site of AChE. | Aminosalicylic Acid | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | In the present study, taking acyclic derivatives of 6-methyluracil as a model AChE inhibitor, we attempted to develop AChE inhibitors that specifically bind to the PAS with weak binding to the active site of AChE. | Aminosalicylic Acid | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | We attempted to increase the size of AChE ligands to restrict specific binding to the PAS of AChE. | Aminosalicylic Acid | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 5 | We attempted to increase the size of AChE ligands to restrict specific binding to the PAS of AChE. | Aminosalicylic Acid | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 6 | Based on molecular docking simulations, it was suggested that compounds bind AChE to the active center as well as to the PAS or only to the PAS. | Aminosalicylic Acid | acetylcholinesterase (Cartwright blood group) | Homo sapiens |