Title : CYP3A4 activity and haloperidol effects in alcohol addicts.

Pub. Date : 2015

PMID : 26639694






2 Functional Relationships(s)
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1 Determination of CYP3A4 activity was performed using high performance liquid chromatography with mass spectrometry (HPLC/ MS) by determination of endogenous substrate of this isoenzyme and its metabolite in urine - the ratio: cortisol/6-beta-hydroxycortisol. 6 beta-hydroxycortisol cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 LIMITATIONS OF THE STUDY: It should be noted that in this research the activity of CYP3A4 was determined using high performance liquid chromatography with mass spectrometry (HPLC/MS) by determination the ratio of cortisol/6-beta-hydroxycortisol for the fist time. 6 beta-hydroxycortisol cytochrome P450 family 3 subfamily A member 4 Homo sapiens