Title : Repositioning of Thiourea-Containing Drugs as Tyrosinase Inhibitors.

Pub. Date : 2015 Dec 2

PMID : 26633377






2 Functional Relationships(s)
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1 We observed that methimazole, thiouracil, methylthiouracil, propylthiouracil, ambazone, and thioacetazone inhibited mushroom tyrosinase. Thioacetazone tyrosinase Mus musculus
2 Both thioacetazone and ambazone significantly inhibited tyrosinase, with IC50 of 14 and 15 muM, respectively. Thioacetazone tyrosinase Mus musculus