Title : Magnolol reduces bleomycin-induced rodent lung fibrosis.

Pub. Date : 2015

PMID : 26629034






2 Functional Relationships(s)
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1 Hodroxyproline content, myeloperoxidase (MPO) activity, tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta (TGF-beta) levels increased in the rat lung tissues after bleomycin administration, while superoxide dismutase (SOD) activity decreased in the rat lung tissues. Bleomycin tumor necrosis factor Rattus norvegicus
2 It partly reversed the bleomycin-induced increase of hydroxyproline content, MPO activity, TNF-alpha and TGF-beta levels in the lung tissues, significantly inhibited the bleomycin-induced decrease of SOD activity, Excessive collagen deposition was also inhibited by magnolol administration. Bleomycin tumor necrosis factor Rattus norvegicus