Pub. Date : 2016 Jan 19
PMID : 26621850
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner. | Tigecycline | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 2 | Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner. | Tigecycline | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 3 | We found that p21 overexpression significantly rescued tigecycline-induced cell proliferation inhibition as well as migration and invasion suppression. | Tigecycline | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 4 | Taken together, our results revealed that the essential role of p21 in the inhibitory effect of tigecycline on proliferation, migration and invasion of melanoma. | Tigecycline | cyclin dependent kinase inhibitor 1A | Homo sapiens |