Title : Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis.

Pub. Date : 2016 Feb

PMID : 26616205






1 Functional Relationships(s)
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1 Among seven xanthine derivatives tested at 50-300muM, caffeine, theobromine and acefylline proved to be the most potent enhancers of in vitro deimination of FLG by PAD1 and PAD3. Theobromine filaggrin Homo sapiens