Title : Testosterone selectively influences protein kinase-C-coupled secretion of proluteinizing hormone-releasing hormone-derived peptides.

Pub. Date : 1989 Jul

PMID : 2661212






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The purpose of the present experiment was to determine whether manipulation of gonadal steroid levels in vivo influenced selectively the in vitro secretion of LHRH and GAP under basal or K+ and phorbol ester (PDBu) stimulation. Steroids gonadotropin releasing hormone 1 Rattus norvegicus
2 Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system. Steroids gonadotropin releasing hormone 1 Rattus norvegicus
3 Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system. Steroids gonadotropin releasing hormone 1 Rattus norvegicus