Title : MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma.

Pub. Date : 2015

PMID : 26606261






3 Functional Relationships(s)
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1 MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma. gemcitabine tumor protein p53 Homo sapiens
2 METHODS: Gemcitabine-resistant variants of two mutant p53 human PDAC cell lines were established. gemcitabine tumor protein p53 Homo sapiens
3 CONCLUSION: Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. gemcitabine tumor protein p53 Homo sapiens