Title : Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation.

Pub. Date : 2016 Feb

PMID : 26597785






2 Functional Relationships(s)
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1 Our aim was to characterize the competition for accessing FADS2 mediated Delta6 desaturation between 16:0 and the most abundant polyunsaturated fatty acids (PUFA) in the human diet, 18:2n-6 and 18:3n-3, to evaluate whether competition may be relevant in other tissues and thus linked to metabolic abnormalities associated with FADS2 or fatty acid levels. Fatty Acids fatty acid desaturase 2 Homo sapiens
2 Our aim was to characterize the competition for accessing FADS2 mediated Delta6 desaturation between 16:0 and the most abundant polyunsaturated fatty acids (PUFA) in the human diet, 18:2n-6 and 18:3n-3, to evaluate whether competition may be relevant in other tissues and thus linked to metabolic abnormalities associated with FADS2 or fatty acid levels. Fatty Acids fatty acid desaturase 2 Homo sapiens