Title : FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity.

Pub. Date : 2015

PMID : 26583035






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Human kidney 2 (HK2) cells were exposed to high glucose with or without the FXR agonist GW4064 or when FXR mRNA was silenced. GW 4064 nuclear receptor subfamily 1 group H member 4 Homo sapiens
2 HK2 cells exposed to high glucose had reduced FXR expression and increased MCP-1, TGF-beta1, fibronectin and collagen IV expression, which was reversed in the presence of GW4064. GW 4064 nuclear receptor subfamily 1 group H member 4 Homo sapiens