Pub. Date : 2014 Apr
PMID : 26579371
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy. | Vemurafenib | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
| 2 | In this review, we highlight some of the recent findings related to the effect of ABC drug transporters such as ABCB1 and ABCG2 on the oral bioavailability of vemurafenib, problems associated with treating melanoma brain metastases and the development of acquired resistance to vemurafenib in cancers harboring the BRAF (V600E) mutation. | Vemurafenib | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
| 3 | In this review, we highlight some of the recent findings related to the effect of ABC drug transporters such as ABCB1 and ABCG2 on the oral bioavailability of vemurafenib, problems associated with treating melanoma brain metastases and the development of acquired resistance to vemurafenib in cancers harboring the BRAF (V600E) mutation. | Vemurafenib | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |