Title : The protective role of isorhamnetin on human brain microvascular endothelial cells from cytotoxicity induced by methylglyoxal and oxygen-glucose deprivation.

Pub. Date : 2016 Feb

PMID : 26578299






1 Functional Relationships(s)
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1 Besides its well-known inhibition on the mitochondria-dependent or intrinsic apoptotic pathway, isorhamnetin also reduced activation of the extrinsic apoptotic pathway, as characterized by the decreased expression and activity of caspase 3 and caspase 8. 3-methylquercetin caspase 3 Homo sapiens