Title : Processing and presentation of insulin. II. Evidence for intracellular, plasma membrane-associated and extracellular degradation of human insulin by antigen-presenting B cells.

Pub. Date : 1989 Jun 15

PMID : 2656861






1 Functional Relationships(s)
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1 The processing of HI both at the plasma membrane and intracellularly was inhibited by chloroquine, monensin, and NH4Cl, suggesting that both intracellular pH changes and endocytic and exocytic events may be required for these compartments to process insulin. Ammonium Chloride insulin Homo sapiens