Pub. Date : 2015 Dec 10
PMID : 26562217
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Development of Alkyne-Containing Pyrazolopyrimidines To Overcome Drug Resistance of Bcr-Abl Kinase. | pyrazolopyrimidines | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 2 | Our results demonstrate that some alkyne-containing pyrazolopyrimidines potently inhibit not only Abl(T315I) in vitro but also Bcr-Abl(T315I) in cells. | pyrazolopyrimidines | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |