Title : Simvastatin ameliorates experimental autoimmune encephalomyelitis by inhibiting Th1/Th17 response and cellular infiltration.

Pub. Date : 2015 Dec

PMID : 26559850






1 Functional Relationships(s)
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1 RESULTS: Simvastatin (5 mg/kg/day) improved clinical outcome, induced an increase in TGF-beta mRNA expression and inhibited IL-6, IL-12p40, IL-12p70, RANTES and MIP-1beta secretion (p < 0.05). Simvastatin transforming growth factor beta 1 Homo sapiens