Title : Multiple Signaling Pathways Contribute to the Thrombin-induced Secretory Phenotype in Vascular Smooth Muscle Cells.

Pub. Date : 2015 Nov

PMID : 26557022






1 Functional Relationships(s)
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1 Co-treatment of HAoSMCs with GF109230X, an inhibitor of protein kinase C, or GW5074, an inhibitor of Raf-1 kinase, caused inhibition of ERK1/2 phosphorylation and significantly attenuated expression of CCL11 at transcriptional and protein levels induced by thrombin. 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone coagulation factor II, thrombin Homo sapiens