Title : Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression.

Pub. Date : 2015

PMID : 26556721






2 Functional Relationships(s)
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1 In the present study, we examined the protective effect of Sch B against intracerebroventricular (ICV)-infused Abeta-induced neuronal dysfunction in rat cortex and explored the potential mechanism of its action. schizandrin B amyloid beta precursor protein Rattus norvegicus
2 Several proteins such as receptor for advanced glycation end products (RAGE), nuclear factor-kappaB, mitogen-activated protein kinases, and apoptosis markers were over expressed in Abeta-infused rats but were significantly inhibited by Sch B treatment. schizandrin B amyloid beta precursor protein Rattus norvegicus