Title : Low levels of graphene and graphene oxide inhibit cellular xenobiotic defense system mediated by efflux transporters.

Pub. Date : 2016

PMID : 26554512






4 Functional Relationships(s)
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1 However, graphene and GO at the nontoxic concentrations could increase calcein-AM (CAM, an indicator of membrane ATP-binding cassette (ABC) transporter) activity) accumulation, indicating inhibition of ABC transporters" efflux capabilities. Graphite ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens
2 However, graphene and GO at the nontoxic concentrations could increase calcein-AM (CAM, an indicator of membrane ATP-binding cassette (ABC) transporter) activity) accumulation, indicating inhibition of ABC transporters" efflux capabilities. Graphite ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens
3 The inhibition of ABC transporters was found to be based on graphene and GO damaging the plasma membrane structure and fluidity, thus altering functions of transmembrane ABC transporters. Graphite ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens
4 The inhibition of ABC transporters was found to be based on graphene and GO damaging the plasma membrane structure and fluidity, thus altering functions of transmembrane ABC transporters. Graphite ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens