Title : Sialic Acid on the Glycosylphosphatidylinositol Anchor Regulates PrP-mediated Cell Signaling and Prion Formation.

Pub. Date : 2016 Jan 1

PMID : 26553874






3 Functional Relationships(s)
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1 In this study, the role of the glycosylphosphatidylinositol (GPI) anchor attached to PrP(C) in prion formation was examined using a cell painting technique. Glycosylphosphatidylinositols prion protein Mus musculus
2 In this study, the role of the glycosylphosphatidylinositol (GPI) anchor attached to PrP(C) in prion formation was examined using a cell painting technique. Glycosylphosphatidylinositols prion protein Mus musculus
3 These findings show that the sialic acid moiety of the GPI attached to PrP(C) modifies local membrane microenvironments that are important in PrP-mediated cell signaling and PrP(Sc) formation. Glycosylphosphatidylinositols prion protein Mus musculus