Title : Novel insights into the regulation of cyclooxygenase-2 expression by platelet-cancer cell cross-talk.

Pub. Date : 2015 Aug

PMID : 26551717






1 Functional Relationships(s)
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1 Platelets are activated by the interaction with cancer cells and release enhanced levels of lipid mediators [such as thromboxane (TX)A2 and prostaglandin (PG)E2, generated from arachidonic acid (AA) by the activity of cyclooxygenase (COX)-1], granule content, including ADP and growth factors, chemokines, proteases and Wnt proteins. Arachidonic Acid mitochondrially encoded cytochrome c oxidase I Homo sapiens