Title : The Protective Effect of INH2BP, a Novel PARP Inhibitor 5-Iodo-6-Amino-1,2-Benzopyrone, Against Hydrogen Peroxide-Induced Apoptosis Through ERK and p38 MAPK in H9c2 Cells.

Pub. Date : 2015

PMID : 26550832






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Taken together, these results demonstrate that INH2BP prevents H2O2-induced apoptosis in H9c2 cells by reducing the production of intracellular ROS, regulating apoptotic-related proteins, and the activation of the ERK1/2 and p38 MAPK. Hydrogen Peroxide mitogen activated protein kinase 3 Rattus norvegicus