Pub. Date : 2015 Dec 15
PMID : 26546608
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation. | Nigericin | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Additionally, the NLRP3 activators nigericin and monosodium urate crystals lowered iATP through K(+)- and Ca(2+)-mediated mitochondrial dysfunction, suggesting a feedback loop between iATP loss and lowering of mitochondrial membrane potential. | Nigericin | NLR family pyrin domain containing 3 | Homo sapiens |