Pub. Date : 2015
PMID : 26545089
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intervention with cyclopamine in ALI mice led to a reduction in mRNA levels of SHH, PTC, and GLI1 as well as SHH and GLI1 protein levels; meanwhile, the pathological injury scores of lung tissues, thickness of alveolar septa, W/D, and mRNA expression levels of TNF-alpha increased compared with mice receiving LPS only. | cyclopamine | GLI-Kruppel family member GLI1 | Mus musculus |
| 2 | Intervention with cyclopamine in ALI mice led to a reduction in mRNA levels of SHH, PTC, and GLI1 as well as SHH and GLI1 protein levels; meanwhile, the pathological injury scores of lung tissues, thickness of alveolar septa, W/D, and mRNA expression levels of TNF-alpha increased compared with mice receiving LPS only. | cyclopamine | GLI-Kruppel family member GLI1 | Mus musculus |