Pub. Date : 2015
PMID : 26528183
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These protumoral activities of lactate depend on lactate uptake, a process primarily facilitated by the inward, passive lactate-proton symporter monocarboxylate transporter 1 (MCT1); the conversion of lactate and NAD(+) to pyruvate, NADH and H(+) by lactate dehydrogenase-1 (LDH-1); and a competition between pyruvate and alpha-ketoglutarate that inhibits prolylhydroxylases (PHDs). | Pyruvic Acid | solute carrier family 16 member 1 | Homo sapiens |