Pub. Date : 2015 Nov 3
PMID : 26525891
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease. | salvianolic acid B | sirtuin 1 | Rattus norvegicus |
| 2 | Importantly, SalB significantly inhibited HMGB1 nuclear translocation and release, accompanied by SIRT1 elevation. | salvianolic acid B | sirtuin 1 | Rattus norvegicus |
| 3 | Moreover, pharmacological SIRT1 inhibition by Ex527 induced HMGB1 translocation and release, whereas SIRT1 activation by resveratrol or SalB reversed this trend. | salvianolic acid B | sirtuin 1 | Rattus norvegicus |