Title : Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol.

Pub. Date : 2016 Feb

PMID : 26514968






2 Functional Relationships(s)
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1 Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 It was demonstrated that CYP2D6 polymorphisms affect the serum concentrations of aripiprazole (n = 18), haloperidol (n = 11), risperidone (n = 20), and zuclopenthixol (n = 6), while no influence was seen on the paliperidone serum concentrations (n = 31). Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens