Title : Double blind, randomised, placebo-controlled trial to evaluate the efficacy of esomeprazole to treat early onset pre-eclampsia (PIE Trial): a study protocol.

Pub. Date : 2015 Oct 28

PMID : 26510725






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Esomeprazole potently decreases soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin secretion from placenta and endothelial cells, and has biological actions to mitigate endothelial dysfunction and oxidative stress. Esomeprazole endoglin Homo sapiens
2 We will examine whether esomeprazole can decrease serum sFlt-1 and soluble endoglin levels and we will record the safety of esomeprazole in these pregnancies. Esomeprazole endoglin Homo sapiens