Title : Human lung cancer-derived immunosuppressive plasmacytoid dendritic cells release IL-1α in an AIM2 inflammasome-dependent manner.

Pub. Date : 2015 Nov

PMID : 26506473






1 Functional Relationships(s)
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1 This effect was observed on the specific activation of the inflammasome absent in melanoma 2 (AIM2), which led to higher cytoplasmic calcium release responsible for calpain activation underlying IL-1alpha release. Calcium interleukin 1 alpha Homo sapiens