Pub. Date : 2016 Jan 12
PMID : 26498361
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVES: This review stated the possible application of the active components of licorice, glycyrrhizin (GL) and glycyrrhetinic acid (GA), in rheumatoid arthritis (RA) treatment based on the cyclooxygenase (COX)-2/thromboxane A2 (TxA2) pathway. | Glycyrrhetinic Acid | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
2 | OBJECTIVES: This review stated the possible application of the active components of licorice, glycyrrhizin (GL) and glycyrrhetinic acid (GA), in rheumatoid arthritis (RA) treatment based on the cyclooxygenase (COX)-2/thromboxane A2 (TxA2) pathway. | Glycyrrhetinic Acid | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
3 | RESULTS: The active components of licorice GL and GA exert the potential anti-inflammatory effects through, at least in part, suppressing COX-2 and its downstream product TxA2. | Glycyrrhetinic Acid | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
4 | CONCLUSIONS: The active components of licorice, GL and GA, could not only potentiate the therapeutic effects but also decrease the adverse effects of NSAIDs or DMARDs through suppressing the COX-2/TxA2 pathway during treatment course of RA. | Glycyrrhetinic Acid | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |