Title : A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes.

Pub. Date : 2015 Dec

PMID : 26497614






1 Functional Relationships(s)
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1 In cultured CFs, Ang II treatment enhanced exosome release via the activation of Ang II receptor types 1 (AT1R) and 2 (AT2R), whereas lipopolysaccharide, insulin, endothelin (ET)-1, transforming growth factor beta (TGFbeta)1 or hydrogen peroxide did not. Hydrogen Peroxide angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus