Title : Co-treatment of THP-1 cells with naringenin and curcumin induces cell cycle arrest and apoptosis via numerous pathways.

Pub. Date : 2015 Dec

PMID : 26496980






2 Functional Relationships(s)
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1 Numerous pathways, including p53, c-Jun N-terminal kinases (JNK), Akt and extracellular signal-regulated kinases (ERK)1/2 pathways were markedly altered following treatment of THP-1 cells with curcumin and naringenin. Curcumin tumor protein p53 Homo sapiens
2 These results indicated that naringenin may enhance curcumin-induced apoptosis through inhibiting the Akt and ERK pathways, and promoting the JNK and p53 pathways. Curcumin tumor protein p53 Homo sapiens