Title : Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX-770 (ivacaftor).

Pub. Date : 2016 Feb

PMID : 26492939






1 Functional Relationships(s)
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1 Functional expression of CFTR was assayed as the forskolin-stimulated short-circuit current (Isc ) across airway epithelial monolayers expressing F508del CFTR. Colforsin CF transmembrane conductance regulator Homo sapiens