Title : Fluorescence biosensing strategy based on mercury ion-mediated DNA conformational switch and nicking enzyme-assisted cycling amplification for highly sensitive detection of carbamate pesticide.

Pub. Date : 2016 Mar 15

PMID : 26492468






1 Functional Relationships(s)
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1 In the presence of carbamate pesticide, the activity of AChE is inhibited, and the amount of the product containing the thiol group generated by the hydrolysis reaction of acetylthiocholine chloride (ACh) decreases, resulting in the release of a low concentration of Hg(2+). Acetylthiocholine chloride acetylcholinesterase (Cartwright blood group) Homo sapiens