Pub. Date : 2015 Oct 20
PMID : 26492244
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We hypothesized that folic acid supplementation modulates DNA methyltransferase (DNMT) activity and may alter amyloid beta-peptide (Abeta) production in AD. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 2 | Furthermore, folic acid decreased Abeta protein production, whereas inhibition of DNMT activity by zebularine increased Abeta production. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 3 | The results indicate that folic acid induces methylation potential-dependent DNMT enzymes, thereby attenuating Abeta production. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |