Title : Attenuation of the macrophage inflammatory activity by TiO₂ nanotubes via inhibition of MAPK and NF-κB pathways.

Pub. Date : 2015

PMID : 26491301






2 Functional Relationships(s)
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1 Following, by using specific MAPK inhibitors, we observed that lipopolysaccharide-induced production of monocyte chemotactic protein-1 and nitric oxide was significantly inhibited on the Ti/TiO2 surface via p38 and ERK1/2, but not via JNK. Nitric Oxide mitogen-activated protein kinase 8 Homo sapiens
2 However, the selective inhibitor for JNK signaling pathway (SP600125) was effective in reducing tumor necrosis factor alpha release as well as monocyte chemotactic protein-1 and nitric oxide production. Nitric Oxide mitogen-activated protein kinase 8 Homo sapiens